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Women make 85 percent of retail purchases, with working women between the ages of 40 and 60 forming the largest market. Although a few companies, including Nautica and Banana Republic, feature mature models in ads or catalogs, older women remain largely invisible in print ads.
Referring to most older models, Lippert says, \"These women are still extremely thin and look fabulous. It's not exactly realistic to think people are going to age this way.\" She would like to see older women and men \"used for products other than bladder control and retirement money and electric mattresses. These older people are vibrant, doing all kinds of things, including buying cars and traveling.\"
Even the use of gray-haired models, she claims, can be a form of tokenism. \"To show you they're representing the older market, they use gray hair,\" Byron says. \"You can be in that older market and have any color hair.\"
Similarly, Dines finds that women of color are also rendered largely invisible in ads. African-American models may be shown in jungle settings or wearing leopard skins and animal prints. If advertisers pick African-Americans, they use models with white features, she says. \"In reality, the model of beauty is whiteness.\"
Excimer laser (KrF excimer laser, 248 nm wavelength) was used to damage cellular components in the dorsal funiculus at the lumbar level (L2) of the rat spinal cord. An open lesion was not found at the irradiation site on the spinal cord. However, the cytological examination revealed that cellular components were damaged to the depth of 200-500 microm from the pial surface. The characteristic feature was that at the border of the lesion, many axons remained naked but intact after their myelin sheaths had been completely disintegrated. Such naked axons were subsequently remyelinated by mature or immature glial cells. Mature oligodendrocytes, while retaining their cytoplasmic processes connected with the myelin sheaths of unaffected axons, extended new cytoplasmic processes on nearby naked axons and made new myelin sheaths around them. In contrast, 7 days after the irradiation, numerous immature glial cells appeared in association with naked axons, and some of them were differentiated into oligodendrocytes forming thin myelin sheaths on naked axons. These findings suggest that demyelinated axons can cause the proliferation and probably dedifferentiation of the oligodendrocyte lineage. The use of lasers provides a unique experimental model of demyelination and remyelination in the central nervous system of adult mammals.
Naked mole-rats are a long-lived rodent species (current lifespan >37 years) and an increasingly popular biomedical model. Naked mole-rats exhibit neuroplasticity across their long lifespan. Previous studies have begun to investigate their neurogenic patterns. Here, we test the hypothesis that neuronal maturation is extended in this long-lived rodent. We characterize cell proliferation and neuronal maturation in established rodent neurogenic regions over 12 months following seven days of consecutive BrdU injection. Given that naked mole-rats are eusocial (high reproductive skew where only a few socially-dominant individuals reproduce), we also looked at proliferation in brain regions relevant to the social-decision making network. Finally, we measured co-expression of EdU (newly-born cells), DCX (immature neuron marker), and NeuN (mature neuron marker) to assess the timeline of neuronal maturation in adult naked mole-rats. This work reaffirms the subventricular zone as the main source of adult cell proliferation and suggests conservation of the rostral migratory stream in this species. Our profiling of socially-relevant brain regions suggests that future work which manipulates environmental context can unveil how newly-born cells integrate into circuitry and facilitate adult neuroplasticity. We also find naked mole-rat neuronal maturation sits at the intersection of rodents and long-lived, non-rodent species: while neurons can mature by 3 weeks (rodent-like), most neurons mature at 5 months and hippocampal neurogenic levels are low (like long-lived species). These data establish a timeline for future investigations of longevity- and socially-related manipulations of naked mole-rat adult neurogenesis.
I am not sure what you mean by \"naked advocacy\" and \"nihilistic disruption\" but I suppose it means that I advocate conventional, traditional, mainstream academic standards, and I think the library at Los Alamos is a better place to find scientific information than Wikipedia. 59ce067264